Researchers develop medical device that dissolves in the body



Scientists develop Implantable Device that can produce Insulin

Bhadra Kamalasanan ,  Onlymyhealth editorial team
Aug 12, 2014

Scientists have developed a certain, new implantable device that can monitor build-up of acid in diabetics as well as produce necessary amount of insulin. Those people who have type 1 diabetes are especially at risk of high acid levels in their body. Their bodies end up not producing insulin, the hormone which regulates blood sugar levels so that the cells cannot really absorb any glucose from the bloodstream. They also have to tap into another energy source i.e. the fat reserves.


insulinIf a person with type 2 diabetes does not notice the lack of insulin or does not seek timely treatment, he/she can die from ketoacidosis, which is a metabolic shock that results from an excess of beta-hydroxybutyrate, a certain acid that supplies muscles as well as brain with energy through the bloodstream.


Keeping the gravity of the situation in mind, the bioengineers from ETH Zurich’s Department of Biosystems Science and Engineering in Basel have now come up with a new implantable molecular device that comprises two modules, namely, a sensor that measures blood pH from time to time and a gene feedback mechanism that produces the needed amount of insulin.


The modules were constructed from different biological components such as proteins and genes. These were then incorporated into cultivated renal cells. The researchers then embedded millions of customized cells in capsules that were used as implants in the body. The device has a pH sensor, which measures the blood’s precise acidity and reacts sensitively to minor deviations from the ideal pH value.


If the pH values fall below 7.35, the sensor can transmit a signal to trigger insulin production. Such low value of pH is specific for type 1 diabetes, though the blood pH is also likely to drop because of alcohol abuse or exercise on account of over-acidification of the muscles, it prevents itself from falling below 7.35.


Once the blood pH has returned to the normal range, the sensor tries to turn itself off and the reprogrammed cells stop insulin production. The invention has already been tested in mice with type 1 diabetes and related acidosis. As for now, the results look promising. The mice seemed to produce the amount of insulin levels naturally and the implant was also compensated for larger deviations in blood sugar.







Video: Researchers Develop Implantable Device To Prevent HIV

Scientists develop Implantable Device that can produce Insulin
Scientists develop Implantable Device that can produce Insulin images

2019 year
2019 year - Scientists develop Implantable Device that can produce Insulin pictures

Scientists develop Implantable Device that can produce Insulin recommend
Scientists develop Implantable Device that can produce Insulin advise photo

Scientists develop Implantable Device that can produce Insulin picture
Scientists develop Implantable Device that can produce Insulin pics

Scientists develop Implantable Device that can produce Insulin Scientists develop Implantable Device that can produce Insulin new photo
Scientists develop Implantable Device that can produce Insulin new pictures

pictures Scientists develop Implantable Device that can produce Insulin
pics Scientists develop Implantable Device that can produce Insulin

Watch Scientists develop Implantable Device that can produce Insulin video
Watch Scientists develop Implantable Device that can produce Insulin video

Communication on this topic: Scientists develop Implantable Device that can produce , scientists-develop-implantable-device-that-can-produce/
Discussion on this topic: Scientists develop Implantable Device that can produce , scientists-develop-implantable-device-that-can-produce/ , scientists-develop-implantable-device-that-can-produce/

Related News


10 Things No One Tells You About Sex As You Get Older
Just in: Your May 2019Horoscope
Gwyneth Paltrow’s 25 Most PretentiousQuotes
Different Types of Yoga: An Overview of Popular Yoga Styles
Quiz: How Strong Are Your Communication Skills as a Couple
25 Runway-Inspired Ways to Style YourBangs
How to Heal Old Wounds
Kevin Ortiz, an executive member of the citys Latino Democratic Club, pointed out the contrast to Salesforces corporate culture and its celebration of Ohana — the Hawaiian word for family. They talk about the Ohana family — we are all one family
Tesla Unveil The Affordable New Tesla Model 3
Is Dissection Common for Neck Cancer
Korean Steak in Lettuce Cups
How to Keep a Canary Groomed



Date: 14.12.2018, 06:44 / Views: 63582