Eplerenone Reduced Heart Failure Risks



Eplerenone

What Is Eplerenone (Inspra)?

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Eplerenone is the generic form of the brand-name medicine Inspra, which is used to treat high blood pressure.

It's also given to improve the chances of survival in certain people with congestive heart failure who've had a heart attack.

Eplerenone belongs to a class of drugs called mineralocorticoid receptor antagonists. It works by blocking the action of a natural substance in the body that raises blood pressure.

This prescription medication can be used alone or in combination with other treatments.

The Food and Drug Administration (FDA) approved eplerenone in 2002. It's marketed as Inspra by Pfizer, Inc.

Eplerenone Warnings

Before starting on eplerenone, let your doctor know if you have, or have ever had:

Your doctor may recommend that you adopt a low-salt diet during your treatment with eplerenone. Follow these instructions carefully.

Tell your doctor you're taking this medicine before having any type of medical or dental procedure.

Keep all appointments with your doctor and laboratory while using eplerenone. Your healthcare provider will want to perform frequent tests to check your body's response to this drug.

Certain drugs shouldn't be used along with eplerenone. Tell your doctor if you're taking any of the following:

Pregnancy and Eplerenone

Tell your doctor if you're pregnant, or plan to become pregnant, before starting on eplerenone.

You'll need to discuss the benefits and risks of taking this medicine during pregnancy.

It's not known whether eplerenone passes into breast milk. Don't breastfeed a baby while using this medicine.

Eplerenone Side Effects

Common Side Effects of Eplerenone

Tell your doctor if any of the following side effects become severe or don't go away:

  • Dizziness
  • Tiredness
  • Mild diarrhea or stomach pain
  • Headache

Serious Side Effects of Eplerenone

Let your doctor know right away if you experience any of the following serious side effects:

  • Chest pain
  • Fast or irregular heartbeat
  • Enlarged or sore breasts in men
  • Abnormal vaginal bleeding in women
  • Severe or persistent dizziness
  • Severe or persistent diarrhea
  • Swelling of the legs, feet, or ankles
  • Vomiting
  • Tingling in the arms or legs
  • Weakness or heaviness in the legs
  • Loss of muscle tone
  • Cold, gray skin
  • Severe lack of energy
  • Confusion
  • Signs of anaphylaxis, which may include rash, hives, difficulty breathing, tightness in the chest, or swelling of the face, mouth, lips, or tongue

Eplerenone Interactions

Tell your doctor about all prescription, nonprescription, illegal, recreational, herbal, nutritional, or dietary drugs you're taking, especially those listed in the Eplerenone Warnings section above, and the following:

Eplerenone and Other Interactions

Eplerenone may cause dizziness.

Don't drive or perform other activities that require alertness until you know how this medicine affects you.

Eplerenone and Alcohol

Alcohol may worsen certain side effects of eplerenone.

Talk to your doctor before drinking alcoholic beverages while using this drug.

Eplerenone and Grapefruit

Grapefruit or grapefruit juice may interact with how eplerenone works in the body.

Talk to your doctor about consuming grapefruit while taking this medicine.

Eplerenone Dosage

Eplerenone comes as a tablet to take by mouth, usually once or twice daily.

It can be taken with or without food.

Your doctor may start you on a low dose of eplerenone and gradually increase it.

Try to take this medicine around the same time each day.

Follow the instructions on your prescription label carefully. Don't take more or less eplerenone than is recommended.

It may take four weeks or longer before you experience the full benefits of this medicine.

Continue to take eplerenone even if you feel well. Don't stop taking it without first talking to your doctor.

Eplerenone Overdose

Symptoms of an eplerenone overdose may include:

  • Dizziness or fainting
  • Blurred vision
  • Upset stomach
  • Tingling in the arms or legs
  • Confusion
  • Lack of energy
  • Cold, gray skin
  • Loss of muscle tone
  • Heaviness or weakness in the legs
  • Slow or irregular heartbeat

If you suspect an overdose, contact a poison control center or emergency room immediately.

You can get in touch with a poison control center at 800-222-1222.

Missed Dose of Eplerenone

If you miss a dose of eplerenone, take it as soon as you remember.

But if it's almost time for your next scheduled dose, skip the missed dose and continue with your regular medication schedule.

Don't take extra medicine to make up for a missed dose.






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Date: 10.12.2018, 18:42 / Views: 52235